Publications

Optic Neuritis: a Model to Test Remyelinating, Neuroprotective Drugs

Martínez-Lapiscina EH, Sanchez-Dalmau B, Fraga-Pumar E, Ortiz-Perez S, Tercero-Uribe AI, Torres-Torres R and Villoslada PThe Visual Pathway As a Model to Understand Brain Damage in Multiple Sclerosis. Mult. Scler. 2014 Nov;20(13):1678-85.

Dynamics of retinal injury after acute optic neuritis

Gabilondo I, Martínez-Lapiscina EH, Fraga-Pumar E, Ortiz-Perez S, Torres-Torres R, Andorra M, Llufriu S, Zubizarreta I, Saiz A, Sanchez-Dalmau B, Villoslada P. Dynamics of retinal injury after acute optic neuritis. Ann Neurol. 2015;77:517-528.

Is the incidence of optic neuritis increasing?

Martínez-Lapiscina EH, Fraga-Pumar E, Pastor X, Gómez M, Conesa A, Lozano-Rubí R, Sánchez-Dalmau B, Alonso A, Villoslada P. Is the incidence of optic neuritis rising? Evidence from an epidemiological study in Barcelona (Spain), 2008-2012. J Neurol. 2014 Apr;261(4):759-67

SGK is a target of the PI3K Pathway

Park J, Leong ML, Buse P, Maiyar AC, Firestone GL, Hemmings BA. Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI3-kinase-stimulated signaling pathway. EMBO J. 1999 Jun 1; 18(11):3024-33.

SGK Mediates Survival by Phosphorilating FOXO3a

Brunet A, Park J, Tran H, Hu LS, Hemmings BA, Greenberg ME. Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)Mol Cell Biol. 2001 Feb; 21(3):952-65.

 

 

 

Neurotrophic Effects of SGK on Dopamine Neurons

Chen X, Tagliaferro P, Kareva T, Yarygina O, Kholodilov N, Burke RE. Neurotrophic effects of serum- and glucocorticoid-inducible kinase on adult murine mesencephalic dopamine neurons. J Neurosci. 2012 Aug 15;32(33):11299-308

 

The Neuronal SGK Reduces Neuronal Excitability

Miranda P, Cadaveira-Mosquera A, González-Montelongo R, Villarroel A, González-Hernández T, Lamas JA, Alvarez de la Rosa D, Giraldez T. The neuronal serum- and glucocorticoid-regulated kinase 1.1 reduces neuronal excitability and protects against seizures through upregulation of the M-current. J Neurosci. 2013 Feb 6;33(6):2684-96.